To improve control of African trypanosomosis in Eastern Africa through investigations of the prevalence and extent of spread, risk of overlap of the two forms of the disease, and the magnitude and nature of melarsoprol resistance.
To identify the reasons for melarsoprol treatment failures in T.b. gambiense and T. b. rhodesiense sleeping sickness patients to enable the development of strategies for the treatment of refractory cases.
To assess the prevalence of sleeping sickness, the distribution of T. b. gambiense and T. b. rhodesiense, and the risk of overlap of the two trypanosome subspecies in specific regions of the network countries.
To assess the risk of spread of T .b. gambiense and T. b. rhodesiense from endemic to other non-affected areas of the network countries by studying the vectorial capacity of Glossina fuscipes fuscipes strains from different regions of East Africa.
To carry out training activities for national capacity building in the field of trypanosome isolation and characterization, conducting field surveys as well as tsetse breeding and transmission studies.
To build up an information network to assure and sustain exchange of information within and beyond the network. Establish regular exchange with health and agricultural extension services to foster communication of research results to the end users.